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Breakthrough Anti-Cancer Herb
Translated by David J. Toman
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Local breakthrough in anti-cancer herbs
discovered
from Taiwan's United Daily News
July 9, 2002
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A major breakthrough has been made in a locally
developed anti-cancer medicine with the Industrial Research Technology
Research Institute's discovery that derivatives of the common
Chinese medical remedy Shan Fang Feng (Ledebouriella) can
effectively suppress the growth of cancer cells. With minimal
or no side effects, Ledebouriella is being touted as the first
locally developed anti-cancer substance found in Chinese herbal
medicine. Current findings have been transferred to a local pharmaceutical
company for pre-clinical studies.
After years of research, the Industrial Research Technology Research
Institute (ITRI) has discovered for the first time an anti-cancerous
local Chinese herbal substance. Working with National Taiwan University
and the National Cancer Institute of the United States, ITRI has
completed active substance follow-up studies, active substance
synthesis, chemical structure refinement, tumor cell activity
screening, and in vivo activity tests in animals, demonstrating
the substance's high selectivity in destroying cancer cells
and its activities against renal, breast, ovarian, and nasopharyngeal
cancer cells.
Ledebouriella (Radix Ledebouriellae), a common Chinese herbal
remedy, is generally used to strengthen the immune system or relieve
rheumatic pains. Working with the active components of the traditional
remedy Shan Fang Feng, the ITRI Biomedical Engineering Center
discovered multiple polythiophene compounds and related derivatives,
and using chemical synthesis techniques was able to obtain an
anti-cancer compound believed to be 10,000 times more effective
in suppressing the activity of cancer cells than the most commonly
used substance, Proleukin.
According to Lee Chung-hsi, deputy director of ITRI, the most
significant characteristic of this compound is a particle structure
completely different from that of previous anti-cancer substances,
thereby opening up completely new possibilities. Highly potent,
the substance must only be used in low dosages to minimize side
effects.
Patients are advised to avoid self-medication with Shan Fang
Feng, as the remedy also contains other toxic substances and must
be taken in combination with other herbs.
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